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Mixture antimicrobienne
Product-No.: 238.001

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Matières Premières:

Produced by supercritical fluid extraction with natural carbon dioxide, for some extracts with addition of a small amount of ethanol as entrainer. Therefore no inorganic salts, no heavy metals, no reproducible microorganisms [1]. The product is a blend of various FLAVEX extracts.

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Oregano contains the active ingredients carvacrol and thymol (also contained in ajwain), which have strong anti-bacterial and anti-fungal effects [2]. Eugenol is an antimicrobially active substance of the clove. It is effective against both Gram-negative and Gram-positive bacteria [3]. Licorice root extract contains antibacterial agents that inhibit the growth of important oral pathogens [4]. The xanthorrizole contained in the curcuma extract is effective against food-borne pathogens such as Clostridium perfringes or Listeria monocytogenes, as well as against bacteria causing caries and periodontitis [5]. The antimicrobial effect of hop extracts in beer production has been known for a long time, especially the growth of gram-positive bacteria and fungi is inhibited by the hop bitters (humulones and lupulones) [6,7]. Sage extract contains the diterpenes carnosol and carnosolic acid, which have antibacterial and antioxidant properties [8,9].*

The Antimicrobial Blend can be used as a spice extract in the food industry due to its spicy fresh flavour. It is particularly suitable for spice mixtures, meat and fish products. Its use in non-alcoholic and alcoholic beverages is also conceivable. Due to its antimicrobial and antioxidative properties, the extract has a natural preservative effect as positive side effect [10,11].*


Due to antimicrobial effect of the extract, it can be used as a natural preservative in various cosmetic products. The extract is particularly suitable for dental care products such as toothpaste and mouthwashes. However, its use in soaps, shower gels and deodorants also matches the properties of the extract.*

[1] P. Manninen, E. Häivälä, S. Sarimo, H. Kallio : Distribution of microbes in supercritical CO2 extraction of sea buckthorn (Hippophae rhamnoides) oils : Zeitschrift für Lebensmitteluntersuchung und -Forschung / Springerverlag (1997) 204: 202-205
[2] Mohammad Y. Memar, Parisa Raei, Naser Alizadeh, Masoud Akbari Aghdam and Hossein Samadi Kafil : Carvacrol and thymol: strong antimicrobial agents against resistant isolates : Reviews in Medical Microbiology 2017, 28:63–68
[3] Coralie Pavesi, Lucy A. Banks and Taghread Hudaib : Antifungal and Antibacterial Activities of Eugenol and Non-Polar Extract of Syzygium aromaticum L. : J. Pharm. Sci. & Res. Vol. 10(2), 2018, 337-339
[4] Stefan Gafner et al. : Isoflavonoids and Coumarins from Glycyrrhiza uralensis: Antibacterial Activity against Oral Pathogens and Conversion of Isoflavans into Isoflavan-Quinones during Purification : J. Nat. Prod., 2011, 74 (12), pp 2514–2519
[5] Lee LY, Shim JS, Rukayadi Y, Hwang JK : Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens : J Food Prot. Sep
71(9):1926-30, 2008.
[6] Langezaal CR et al. : Antimicrobial Screening of essential oils and extracts of some Humulus lupulus L.cultivars : Pharmceutisch Weekblad. Scientific Ed. 14, 353, 1992
[7] Marcel Karabín, Tereza Hudcová, Lukás Jeíınek and Pavel Dostálek : Biologically Active Compounds from Hops and Prospects for Their Use : Comprehensive Reviews in Food Science and FoodSafet, Vol.15, 2016
[8] Simona Birtic, Pierre Dussort, François-Xavier Pierre, Antoine C. Bily, Marc Roller : Carnosic acid : Phytochemistry 115 (2015) 9–19
[9] S. Weckesser, K. Engel, B. Simon-Haarhaus, A. Wittmer, K. Pelz, C.M. Schempp : Screening of plant extracts for antimicrobial activity against bacteria and yeasts with dermatological relevance : Phytomedicine,14 (2007) 508-516
[10] Marko Tarvainen, Anu Nuora, Karl-Werner Quirin, Heikki Kallio, Baoru Yang : Effects of CO2 plant extracts on triacylglycerol oxidation in Atlantic salmon during cooking and storage : Food Chemistry 173 (2015) 1011–1021
[11] H.-L. ALAKOMI, J. MAUKONEN, K. HONKAPAA ,E. STORGA RDS, K.-W. QUIRIN, B. YANG AND M. SAARELA : Effect of Plant Antimicrobial Agents Containing Marinades on Storage Stability and Microbiological Quality of Broiler Chicken Cuts Packed with Modified Atmosphere Packaging : Journal of Food Protection, Vol. 80, No. 10, 2017, Pages 1689–1696

* Statements summarise literature evidence and have informative character. They might be derived from in vitro or animal tests and thus not be substantiated for humans. Statements have not been evaluated by competent authorities and do not refer to finished products. The marketer of any finished product containing any FLAVEX extract as ingredient is responsible for assuring that the claims made for his product are lawful and comply with all applicable laws and regulations of the country in which the product is to be sold.